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My choice is to start Tamoxifen or not. Should I?

6/21/2020

I'm 40. I've had two breast biopsies, one small and one large. My cells were abnormal, but not breast cancer. My choice is to start Tamoxifen or not. Should I?

“If a patient had multiple biopsies in the past, and they are concerned about breast cancer risk, then they can talk to their surgeon or a family doctor, or a high-risk clinic and find out what exactly is their risk for developing breast cancer in the future.

That depends on multiple factors. Actually, we use a scale, known as Gail risk model, to calculate the risk of developing breast cancer for the next five years. And that's only used for patients, who older than 35. So, Gail risk model includes the age of the patient, age of menarche, what age they had the first period, age and the first live both, then, of course, how old they are, family history. And if they had any biopsies in the past, and if the biopsy showed any abnormal finding, so these five factors will allow us to calculate that person's risk of developing for breast cancer for the next five years.

My choice is to start Tamoxifen or not. Should I?

If that's more than 1.7 %, that's considered as a high risk, so there are large randomized studies, which, actually, looked at patients, who are high-risk that means more than 1.7 % of Dalton breast cancer for the next five years.

We were using two medicines: Tamoxifen and Raloxifene. Raloxifene is used mainly in postmenopausal patients. So, these anti-acid medicines are to cut down the chance of breast cancer by fifty percent. So, again, if you have biopsies, if you have strong family history, then it is important for you to talk to your doctor and understand what the risk of developing breast cancer is and how you can prevent that.”

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