So, to shine UK we've adopted a slightly different approach to the drug development, and we're looking at repurposing, which is when you take a drug that's already been approved for use in a different disease like cancer, and you test it to see if it's going to have efficacy in Duchenne muscular dystrophy.
Many of the European agencies have recommended that women should consider taking the drug for an extra five years. And without this test we know that we can't predict exactly who is going to benefit for the extra five years. So, as we have in the past, we tend to offer this to all women. Our many oncologists do that.
We did a phase three trial of low-dose Tamoxifen, which is an anti entered estrogen, to prevent recurrence within women, who had a non invasive breast cancer, which can be an atypical ductal hyperplasia, a nobuler or ductal carcinoma site. These forms are very common today with the introduction of screening mammography. At least 20% of all breast neoplasms are intrepid illionaire pleasure.
Rationale for use and how this drug can be used with men that are using anabolic steroids
Is number one – gynecomastia. Okay, that can be used on men that are on TRT and even suffering with steroids. The effects of this drug do block the initial phases of gynecomastia before there is a physical lump.
Most importantly. And this comes from the FDA. I'll compare and contrast the FDA says severe side effects of this drug are strokes, DVTs and developing clots. Classically in the lower limbs that can go up into the lungs it's called a pulmonary embolism it could be very deadly.
Hormone receptor-positive breast cancer. It's interesting that this was the first drug that was used and then a decade or so later came anastrozole of aromatase inhibitors and there's been substantial reports and studies showing that for most women anastrozole aromatase inhibition is actually better and more protective for treating breast cancer.
This is another classic anti estrogen that's been used by the bodybuilding community and men that are using anabolic androgenic steroids for many years. Actually, since the 1990s.
The utility of this drug is more focused than the other drugs. This is specifically for uncycle or PCT gynecomastia and specifically as a regimen with other drugs for post cycle therapy.
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